Pharma Cold Chain
ULT Vaccine & Biologics Biobank — Singapore
Regional biobank for a life-sciences group: ULT −70 °C vaccine storage, GDP 2–8 °C rooms and validated cold-chain logistics.
Location
Singapore
Capacity
120 × ULT freezers · 480 m² cleanroom
Temperature
−70 °C ULT, −20 °C, +2/+8 °C GDP
Budget
USD $14M–$19M
Timeline
11 months
Project overview
A Southeast Asian life-sciences group commissioned ColdMatch Group to structure the tender for its regional biobank in Singapore. The facility supports vaccine trials, biologics and cell-and-gene therapy samples under WHO GDP and PIC/S GMP standards.
Challenge
- ULT temperature integrity across 120 freezers and long power-quality events.
- GDP + PIC/S dual-standard validation required from commissioning.
- Tight urban plot: refrigeration heat rejection had to meet BCA envelope rules.
Solution
- Redundant N+1 ULT freezer strategy across 3 refrigerant families.
- IQ/OQ/PQ protocols aligned to WHO PQS and PIC/S PE 009.
- Water-cooled condensers with heat recovery to domestic hot water loop.
Result
- Zero temperature excursions in first 18 months of operation.
- Regulator granted GDP + PIC/S approval on first inspection.
- 20% lower cooling energy intensity vs. air-cooled baseline.
Scope of works
- ULT −70 °C freezer array (120 units)
- GDP 2–8 °C validated cold rooms
- 24/7 wireless monitoring and alarming
- IQ/OQ/PQ commissioning and validation
- Backup power (UPS + diesel) and BMS
Project gallery
Related capability
Learn more about the sourcing hub behind this project:
Explore Pharma Cold Chain
